How to remove a substring from a string based on list of strings

I have a list of strings(colors), say

l = ['chocolate brown','brown','chocolate']

I have a string:

str = "The jeans is chocolate brown in color and has brown colored pockets"

I have to remove chocolate brown and brown from the list. This is just an example. Basically whenever I encounter a color in a string I have to remove it if it exists in the list of colors. What is the efficient way to do it?