Regex Inverse of String

I've read many places that its either impossible or inefficient to do inverse matching with Regex but,

I know its possible to Match any WHOLE LINE that DOES NOT contain a specified Pattern or String using:

^((?!PatternOrString).)*$

But I want to match any CHARACTER(s) (Even those on the same line as the inverse match) that DO NOT contain a specified pattern and/or string.

I've used this code for a while:

\b((?!String).)*\b

But it seems to have trouble with regex patterns, only working with simple alpha-numeric strings

Is there any way to use something similar to the above which can use regex patterns?

I've tried putting the pattern in a group \b((?!(Pattern)).)*\b but that seems to give me mixed results.